Comprehensive 4D robustness evaluation for pencil beam scanned proton plans
نویسندگان
چکیده
منابع مشابه
Golden beam data for proton pencil-beam scanning.
Proton, as well as other ion, beams applied by electro-magnetic deflection in pencil-beam scanning (PBS) are minimally perturbed and thus can be quantified a priori by their fundamental interactions in a medium. This a priori quantification permits an optimal reduction of characterizing measurements on a particular PBS delivery system. The combination of a priori quantification and measurements...
متن کاملGATE as a GEANT4-based Monte Carlo platform for the evaluation of proton pencil beam scanning treatment plans.
Active scanning delivery systems take full advantage of ion beams to best conform to the tumor and to spare surrounding healthy tissues; however, it is also a challenging technique for quality assurance. In this perspective, we upgraded the GATE/GEANT4 Monte Carlo platform in order to recalculate the treatment planning system (TPS) dose distributions for active scanning systems. A method that a...
متن کاملBeam‐specific planning target volumes incorporating 4D CT for pencil beam scanning proton therapy of thoracic tumors
The purpose of this study is to determine whether organ sparing and target coverage can be simultaneously maintained for pencil beam scanning (PBS) proton therapy treatment of thoracic tumors in the presence of motion, stopping power uncertainties, and patient setup variations. Ten consecutive patients that were previously treated with proton therapy to 66.6/1.8 Gy (RBE) using double scattering...
متن کاملEffects of anatomical changes on pencil beam scanning proton plans in locally advanced NSCLC patients.
BACKGROUND AND PURPOSE Daily anatomical variations can cause considerable differences between delivered and planned dose. This study simulates and evaluates these effects in spot-scanning proton therapy for lung cancer patients. MATERIALS AND METHODS Robust intensity modulated treatment plans were designed on the mid-position CT scan for sixteen locally advanced lung cancer patients. To estim...
متن کاملComprehensive proton dose algorithm using pencil beam redefinition and recursive dynamic splitting
We describe a new pencil beam (PB) algorithm that computes, from first principles, absolute fluence or dose per incident proton charge in a known heterogeneous terrain irradiated by known proton beams. PB transport is by standard Fermi-Eyges theory. Heterogeneites are handled by breaking up PBs using redefinition and recursive dynamic splitting. The terrain is discretized into uniform or hetero...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Radiotherapy and Oncology
سال: 2019
ISSN: 0167-8140
DOI: 10.1016/j.radonc.2019.03.037